Fasting-Imitating Diet May Reverse Diabetes
So many people around the world suffer from diabetes. Scientists are constantly making efforts to find out ways to combat this life-threatening disease. Recently, a group of scientist at the USC Leonard Davis School of Gerontology has designed a diet to mimic the impact of fasting does to revert diabetes by reprogramming the cells. As per the study performed on human and mice cells, the fasting-mimicking diet helps in the production of new insulin-producing pancreatic cells that decrease the signs of type 2 and type 1 diabetes.
Valter Longo, said, “Cycles of a normal diet and fasting-like diet basically reprogrammed the non-insulin-producing cells into insulin-producing cells. By stimulating the rejuvenation of pancreatic cells, it was possible to save the mice from late-stage type 2 and type 1 diabetes. We also re-stimulated the insulin generation in pancreatic cells of human from the patient suffering from type 1 diabetes. The reprogrammed adult organs and cells provoked a regeneration through which the injured cells were substituted with new functional cells.”
Reversing insulin reduction and resistance
The pancreas loses the insulin-producing β cells in the late-stage type 2 and type 1 diabetes, thus elevating flux in the levels of blood sugar. The study demonstrated a significant reverse of diabetes after the mice were kept on the fasting-like diet for 4 days every week. The mice recovered normal insulin production, decreased insulin resistance, and hence, showed more steady blood glucose levels. The same results were observed in the mice with the late-stage disease. The diet cycles were able to turn on the genes in the adult mice that are usually active during the developing stage of pancreases in fetal mice. The genes turned off the production neurogenin-3, which led to the production of new and healthy insulin-producing β cells.
Surely, this study will provide new aspects of treating people suffering from diabetes and enhance their quality of life. Don’t you think so?